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Santa Cruz Biotechnology
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Proteintech
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ABclonal Biotechnology
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Genecopoeia
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Rac1-2-3 Antibody (YA6751) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rac1-2-3.
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Image Search Results
Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Article Title: Exosomal Micro‐RNA‐96 Derived From Bone Marrow Mesenchymal Stem Cells Inhibits Doxorubicin‐Induced Myocardial Toxicity by Inhibiting the Rac1/Nuclear Factor‐κB Signaling Pathway
doi: 10.1161/JAHA.120.020589
Figure Lengend Snippet: Primer Sequences
Article Snippet: After being confined in bovine serum albumin, the proteins were incubated with primary antibodies of
Techniques:
Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Article Title: Exosomal Micro‐RNA‐96 Derived From Bone Marrow Mesenchymal Stem Cells Inhibits Doxorubicin‐Induced Myocardial Toxicity by Inhibiting the Rac1/Nuclear Factor‐κB Signaling Pathway
doi: 10.1161/JAHA.120.020589
Figure Lengend Snippet: A and B , The expression of Rac1 in the myocardium measured by quantitative real time polymerase chain reaction and Western blotting. C , the levels of p‐IKKα, p‐IKKβ, p‐IκBα, and p‐p65 measured by Western blotting; 8 rats for each group. Exo+inhibitor indicates exosome plus inhibitor; Exo+mimic, exosome plus mimic; Exo+miR‐96, exosome plus microRNA‐96; and negative control (NC). * P <0.05, compared with the normal group; ‡ P <0.05, compared with the doxorubicin group; † P <0.05, compared with the exosome+mimic NC group; and § P <0.05, compared with the exosome+inhibitor NC group; data were presented as mean±SD; data were analyzed using 1‐way ANOVA and the Tukey test was applied for post hoc multiple comparisons.
Article Snippet: After being confined in bovine serum albumin, the proteins were incubated with primary antibodies of
Techniques: Expressing, Real-time Polymerase Chain Reaction, Western Blot, Negative Control
Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Article Title: Exosomal Micro‐RNA‐96 Derived From Bone Marrow Mesenchymal Stem Cells Inhibits Doxorubicin‐Induced Myocardial Toxicity by Inhibiting the Rac1/Nuclear Factor‐κB Signaling Pathway
doi: 10.1161/JAHA.120.020589
Figure Lengend Snippet: A , The expressions of micorRNA‐96 and Rac1 in H9c2 cells. B , The protein level of Rac1. C , The levels of p‐IKKα, p‐IKKβ, p‐IκBα, and p‐65 in H9c2 cells; n=3. Exo+inhibitor indicates exosome plus inhibitor; Exo+mimic, exosome plus mimic; Exo+miR‐96, exosome plus microRNA‐96; and NC, negative control. * P <0.05, compared with the control group; ‡ P <0.05, compared with the doxorubicin group; † P <0.05, compared with the exosome+mimic NC group; and § P <0.05, compared with the exosome+inhibitor NC group; $ P <0.05, compared with the exosome+miR‐96 inhibitor+NC siRNA group; data were presented as mean±SD; data were analyzed using 1‐way ANOVA and the Tukey test was applied for post hoc multiple comparisons.
Article Snippet: After being confined in bovine serum albumin, the proteins were incubated with primary antibodies of
Techniques: Negative Control, Control
Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Article Title: Exosomal Micro‐RNA‐96 Derived From Bone Marrow Mesenchymal Stem Cells Inhibits Doxorubicin‐Induced Myocardial Toxicity by Inhibiting the Rac1/Nuclear Factor‐κB Signaling Pathway
doi: 10.1161/JAHA.120.020589
Figure Lengend Snippet: A , TargetScan predicted the sequences of the binding sites between microRNA‐96 and Rac1. B , Dual‐luciferase reporter assay verified the targeting relationship between microRNA‐96 and Rac1 (n=3); data were presented as mean±SD and analyzed by the student t ‐test. miR‐96 indicates microRNA‐96; MUT, mutated‐type; NC, negative control; and WT, wild‐type.
Article Snippet: After being confined in bovine serum albumin, the proteins were incubated with primary antibodies of
Techniques: Binding Assay, Luciferase, Reporter Assay, Negative Control